attana - sensor technologies

Processes

Attana’s biosensors provide access to biologically relevant information of highest quality. Whether the question is to quality control the production line of a biological pharmaceutical or to gain insight into advanced dynamic features of target molecules, Attana biosensors will provide the critical information. Presented below is information how Attana systems can improve specific processes or contact us directly and we will tell you more.

Physiological relevant information selection

Study target interactions in their native environment and select only candidates with biologically relevant properties for downstream in vivo applications.

Drugability determination

Look into new dimensions of biological significance with the Attana QCM systems and increase the success rate in the design and discovery of new therapeutic compounds.

Binding Characterization

Characterize the binding events from both a biochemical and a cell-based assay is essential in order to understand the details of the underlying biological mechanism.

Characterization & Selection

Characterize and select the successful candidates as early as possible in the discovery process by biologically relevant information and generate a faster and cheaper process.

Target ID & validation

Proper drug target selection and validation are crucial to the discovery of new drug candidates in order to generate a faster track to drugability.

Immunogenicity

Measure the full binding profile of the drug-receptor interaction direct in serum or plasma samples to obtain information about the immune response.

Pharmacodynamics

Obtain information about the underlying biochemical and physiological effects of the PD by measuring the full binding profile of the drug-receptor interaction.

Pharmacokinetics

Investigate the full binding profile of the drug-receptor interaction and obtain information about the underlying biochemical and physiological effects of the PK.

Antibody drug response

Measure the full binding profile of the drug-receptor interaction direct in serum or plasma samples to fully understand the details about the ADA response of the immune system.

Thermodynamic characterization

Investigate the processes that involve changes in temperature, transformation of energy, and the relationships between heat and work by thermodynamic analysis of molecular interactions.

Surface chemistry development

Obtain full binding kinetics of a modified chemical composition of a surface to its ligand and understand the interaction to be studied within the surface chemistry development process.

Assay development

The label-free Attana QCM systems are powerful tools in assay development and provide endless possibilities for evaluation binding events when developing diagnostic tools, such as ELISA kits and immunoassays.

Quality control

High quality and efficacy are keys in any process in order to achieve maximum cost efficiency and to ensure success in drug development and manufacturing quality control (QC).

Purification

Save time and money by using the Attana´s QCM systems that bypass the need for purification steps since uncleared crude and serum containing samples can directly be analyzed in the biosensors.

Biomarker analysis

Attana’s QCM-based biosensors are excellent tools for quantification and characterization of biomarkers, combining high sensitivity and high quality analysis for both biochemical and cell-based assays.