attana - sensor technologies

“Predictive separation of biopharmaceuticals for faster drug development,” a new collaboration between Astra Zeneca, Waters Nordic, Attana & Karlstad University

The Swedish Knowledge Foundation (KK-stiftelsen) has awarded AstraZeneca, Waters Nordic, Attana and Karlstad University a grant for an R&D project for predictive separation of biopharmaceuticals for faster drug development.

Stockholm, January 26th, 2016 – The development of new biological medicines is a growing area of high importance for the Swedish pharma industry, as illustrated by the announcement in May 2015 from AstraZeneca that they will invest approximately 285 million USD in a new high-tech facility for manufacturing of biological drugs in Södertälje, Sweden.

In order to develop new biopharmaceuticals it is of high importance to produce biopharmaceutical molecules of high purity and quality for R&D, clinical testing and manufacturing. This project’s major goal is to obtain detailed understanding of the kinetics and thermodynamics of peptide adsorption in order to develop improved and predictive separation methods for production of biopharmaceutical molecules.

Under the guidance of Astra Zeneca and Karlstad University the project will utilize the chromatography technology and knowledge of Waters combined with the label-free biosensor technology and knowledge of Attana to reach the project goal. The project is divided in three sub-projects:

- Utilization of linear methods for acquiring basic parameters for separation behavior of peptides,

- Expanded non-linear methods for detailed adsorption behavior on modern separation media,

- Unified approach to develop methods fulfilling modern quality assurance criteria.

“This project combines world-leading expertise in drug development and interaction characterization and forms a good base for future successful development of biopharmaceuticals,” Prof. Fornstedt (Karlstad University).

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About Attana:

Attana was founded in 2002 with the vision of in-vitro characterization of molecular interactions mimicking in-vivo conditions. Since then, Attana has developed proprietary label free biosensors for biochemical, crude, sera and cell-based assays. Attana’s products and research services are used by Big Pharma, biotech companies and academic institutions within the life sciences. Attana Movie