attana - sensor technologies

Characterization & Selection

To recognize and eliminate clones of poor quality as early as possible in the discovery process, more time and money can be spent characterizing and selecting the candidates with relevant features, generating a faster and cheaper process.

Success in clinical trials is dependent on correct information about the drug candidate and its biological target interaction. Failure, on the other hand, is often due to a lack of relevant information in the selection process. The Attana biosensors that are based on the mass dependent and proximity independent QCM technology are powerful tools for the improved characterization and selection of drug candidates since they have been developed specifically for studying target interactions in their true environment and only those candidates with biologically relevant properties will be selected for downstream in vivo applications. This means that the interactions are studied label-free, under a continuous flow, directly with complex crude biological samples under temperature controlled conditions and this can be done directly on cells with the Attana Cell 200 instrument to obtain a surrounding as close as possible to the in vivo environment within the biosensor enhancing a faster track to drugabiltiy.