Attana Cell 200
Kinetics on cells – bridging the gap between biosensors and cell based assays.
The Attana Cell 200 is a label free, dual channel, temperature controlled, continuous flow system for automated (Attana Cell A200) or manual (Attana Cell 200) analysis of molecular interactions with cells. The system is delivered operation ready and includes: instrument, sensor chips, computer, software and accessories such as syringes, vials and buffer bottles.
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Attana Cell 200 Cell and biochemical assays Analyte/ligand types: - Adherent cells - Suspension cells - Fixed and non-fixed cells - Crude samples - Large sample mass - Proteins, antibodies, carbohydrates - Viruses, bacteria Applications: - Kinetics on cells - Cell capturing - Detailed kinetics - Concentration determination - Competition assay - Epitope mapping - Off-rate selection - Monitor immune response - Aggregation characterization |
Video - Attana Cell 200 Biosensor
Biological Relevance
The Attana Cell 200 enables kinetic characterization of interactions on intact cells, in real time. Cells can be cultivated directly on Attana’s proprietary cell surface or captured from cell suspension before analysis. As the instrument is temperature controlled and uses continuous flow, interactions can be studied at physiological conditions such as normal salinity, 37˚C and under various flow rates. The QCM technology is label free and has no need for secondary detection. Thus, the Attana Cell 200 system offers to study the molecules unmodified, directly and in their natural environment.
High Quality Data
As the ligand interacts with the intact cell in real time, the data captures the complete dynamics and complexity of the interaction, generating data of high information content. The ability to cultivate, treat and analyze the cells directly on the sensor surface minimizes handling and perfects cell conditioning. Two parallel channels give the possibility to run the experiment in duplicate or use one channel as external reference. Automation, precise temperature control, robust fluidics and temperature controlled sample storage avoids user artifacts and ensures system stability and sample integrity. Thus, the Attana Cell 200 delivers secure data of the highest possible quality.
